Seattle variance

Researchers in Ohio this week also reported the discovery of two distinct variants that appear to have emerged in the U. Viral sequencing in Washington is conducted by two academic groups. The UW Medicine Virology Lab aims to sequence to genomes a week out of the thousands of samples sent to the lab for diagnostic testing, said computational biologist Pavitra Roychoudhury. Researchers at the Brotman Baty Institute are getting back online after shutting down for several weeks to switch to a cheaper, faster sequencing system, said Starita.

The sequences are shared in a national repository coordinated by scientists at the Fred Hutchison Cancer Research Center and other institutions. Since most samples come from the Puget Sound area, that leaves big blind spots in other parts of the state, Starita said. The UW Virology group has to juggle sequencing with its more pressing mission of processing diagnostic tests, said assistant director Alex Greninger.

Genomes are sequenced in batches that take three to five days to run. Roychoudhury and her colleagues recently found themselves scrambling to find enough freezer space for specimens. A new CDC program is offering grants to boost sequencing and help fill in the gaps, and scientists hope the incoming Biden administration will make it a higher priority, Starita said.

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